The polyfill.js is a popular open source library to support older browsers. 100K+ sites embed it using the cdn.polyfill.io domain. Notable users are JSTOR, Intuit and World Economic Forum. However, in February this year, a Chinese company bought the domain and the Github account. Since then, this domain was caught injecting malware on mobile devices via any site that embeds cdn.polyfill.io. Any complaints were quickly removed (archive here) from the Github repository.
They’re widely variable. PyPI gets into about as much trouble as npm, but I haven’t heard of a successful attack on CPAN in years (although that may be because no one cares about Perl anymore).