Researchers say experimental shot is step towards goal of creating vaccines before a pandemic has started

Scientists have created a vaccine that has the potential to protect against a broad range of coronaviruses, including varieties that are not yet even known about.

The experimental shot, which has been tested in mice, marks a change in strategy towards “proactive vaccinology”, where vaccines are designed and readied for manufacture before a potentially pandemic virus emerges.

The vaccine is made by attaching harmless proteins from different coronaviruses to minuscule nanoparticles that are then injected to prime the body’s defences to fight the viruses should they ever invade.

Because the vaccine trains the immune system to target proteins that are shared across many different types of coronavirus, the protection it induces is extremely broad, making it effective against known and unknown viruses in the same family.